In this study it was revealed that performance of the POC devices was good for some parameters, while insufficient for other parameters. However, not all POC devices give comparable results as shown by a recent study comparing 2 POC blood gas analyzers to a stationary one in horses. The utilization of portable Point-of-Care (POC) devices provides immediate measurement results for stall-side testing in the clinic and in a field setting. Monitoring of acid-base and electrolyte status in exercising horses is also of clinical use with horses undertaking high-intensity exercise such as racing, eventing or endurance competitions often developing alterations in acid-base and electrolyte status leading to disorders such as exercise-induced dehydration, cardiac dysrhythmias, laminitis or exertional rhabdomyolysis. Assessment of acid-base and electrolyte concentration also provides useful information for the diagnosis and management of metabolic disorders in critically ill horses, horses with gastrointestinal disorders and hereditary conditions (e.g., hyperkalemic periodic paralysis, recurrent exertional rhabdomyolysis) in which alterations of blood electrolyte concentrations are commonly observed. Arterial blood gas analysis enables the assessment of pulmonary oxygenation efficiency and ventilation status, which may be of clinical value for the monitoring of patients under general anesthesia, patients with thoracic or respiratory diseases as well as critically ill neonates. This does not alter our adherence to PLOS ONE policies on sharing data and materials.Īwareness of acid-base and/or electrolyte abnormalities in equine medicine influence the choice of treatment and prognosis, with frequent monitoring of acid-base and electrolyte values in horses allowing early detection and intervention. įunding: The authors received no specific funding for this work.Ĭompeting interests: One of the authors (KK) is employed by an institution that has received sponsorship by IDEXX. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: Full set of data available at. Received: DecemAccepted: JanuPublished: February 15, 2019Ĭopyright: © 2019 Kirsch et al. Katz, University College Dublin, School of Veterinary Medicine, IRELAND The epoc delivered reliable results for and, while results for pH, pCO2, pO2 and should be interpreted with caution.Ĭitation: Kirsch K, Detilleux J, Serteyn D, Sandersen C (2019) Comparison of two portable clinical analyzers to one stationary analyzer for the determination of blood gas partial pressures and blood electrolyte concentrations in horses. The VetStat analyzer may be useful in performing blood gas analysis in equine samples but analysis of, and pO 2 should be interpreted with caution. The VetStat analyzer yielded results that were in agreement with the cobas b 123 analyzer for determination of pH, pCO 2, bicarbonate () and potassium concentration, while the epoc analyzer achieved acceptable agreement for and. Limits of agreement indicated relevant bias between the VetStat and cobas b 123 for partial pressure of oxygen (pO 2 27.5–33.8 mmHg), sodium ( 4.3–21.6 mmol/L) and chloride concentration ( 0.3–7.9 mmol/L) and between the epoc and cobas b 123 for pH (0.070–0.022), partial pressure of carbon dioxide (pCO 2 3.6–7.3 mmHg), pO 2 (36.2–32.7 mmHg) and (0.38.1 mmol/L). Blood gas analysis and electrolyte concentrations measured by the portable analyzers VetStat and epoc were compared to those produced by the cobas b 123 analyzer via concordance analysis, Passing-Bablok regression and Bland-Altman analysis. Blood samples from 23 horses hospitalized for various medical reasons were included in this prospective study. The aim of this study was to determine whether 2 portable analyzers produce results in agreement with a stationary analyzer. Portable blood gas analyzers are used to facilitate diagnosis and treatment of disorders related to disturbances of acid-base and electrolyte balance in the ambulatory care of equine patients.
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